1.21 bug(?) - Controls are sometimes unresponsive

[Phaser Rave]

Version: 1.21 (it's happened for me since release)
Modified: No.
Game start: Tutorial.
DxDiag: https://pastebin.com/raw/72vVMz8L
VulkanInfo: https://pastebin.com/raw/4ah84LQT
Bug description: After a random period of running the game, none of the keys on the keyboard will respond to any input. Sometimes not even the mouse, though typically it will still work. Sometimes during this, I might be able to access the menu by clicking on the icon at the top of the screen, but a few times I have seen that it wouldn't let me save the game.

As for the cause, I do not know how to reproduce it. It appears to be mostly random, but I have noticed it happens more often while I am using the shift, tab, or shift+1 keys, even though I can use them for hours without this bug appearing.

This might be related, but I've noticed that it happens when teleporting, every time. Not even the mouse will respond. I think this is different, because it tends to give back control after a minute or so after teleporting.

This is probably relevant. I have the game installed on an external SATA drive as I do not have enough space on my SSD. Would the game fare better on an SSD?

[Hardie]

not sure if mine are the exact same that you have:
1. Pressing shift + D again (immediately) while undocking leaves the ship hanging above the docking area, unable to move. getting up from the pilot seat and sitting back down fixes the problem.
2. no acceleration with mouse wheel or traveldrive working: dont know how to reproduce, appears randomly (not very often as of 1.21 so not sure about it. Pressing Esc twice fixes the problem.

[Kryten42]

I had that problem with the acceleration too, but I am not sure if its fixed in 1.21, since I haven't played a lot the last days.
It happened three times on my play (8h) so far and when it happens I can still control the steering of the ship, but no matter what I do I cannot accelerate. After pressing a lot of buttons and going into the game menu, the problem goes away eventually. This is really annoying if it happens during a fight!

[Phaser Rave]

I have figured out how to reproduce my issue. Shift + tab seems to be the culprit. I am using the GOG version, and I don't see an overlay for GOG Galaxy when I press those keys like with Steam (I don't believe it has one, does it?). Upon pressing it, it turns the cursor to my regular window's cursor, and seemingly fixes the issue when I repeat the action.