Just now, replaying with 1.22 beta I notice things that weren't functioning or simply missing.
Here is the list so far what is different:
1. I didn't notice before that the distilliation station in Devries supposed to be functional , because the lower part of the station was destroyed, as well as the selling dock was missing or destroyed (?) . I thought, that's how it supposed to be, until just now as I am replaying, the damn thing is able to sell water!
I know some probably didn't have this problem, but I did and I played over 50hrs while Devries couldn't even have water, unless I would have built a new water station!
2. Upon entering Tornid Veil (or close by) the first time during the plot, there is a small freighter asking for help for escorting. I didn't have that the first time i played it.
3. Gushing Springs - My food rations dock was destroyed after I delivered the plot-food ration run. I came back at a certain point, and the whole section was burned out with no food rations selling dock. No wonder, that beside not having water to sell, there isn't even food rations to sell from I couldn't get anywhere!
4. After the rescue of the Canteran freighter from the raiders, there is an award of a small freighter. The first time I got a water trader, but it disappeared after I traveled to another zone and I could never find it.
This time (with the replay of 1.22beta) , I got an energy trader and I already made about 5 runs of energy sales. in Glairing Truth.
.................
So far, this is my list of problems by continuing the plot throughout the patches, I won't mention of course the freezes, crashes and trading problems that I did notice.
So far, I have noticed 2 things that are still not functioning well:
1. Energy selling stations don't stay in the trading computer. Not sure how the others stay in it or they don't , so far I only noticed the energy list (stations selling) being completely empty. After visiting5-6 different energy cell solar plants, none stayed in my trading computer. For example: Just after hanging out and scanning the whole solar plant in Fervid Corona, within a minute- after traveling to Darn Hot Air, the trading option to buy from this station was already missing. Of course, all the other ones too, scanned earlier (about an hour earlier, back in Albion).
Beside this, I still get slow-downs , but I'm glad, that I can actually trade "something" in Glaring Truth sector!
Still, my biggest gripe is loosing trading info. It just escapes me, why is this necessary to have us loose our trading info. Unless if it's a bug.
I mean, come on. Even today, If I buy stuff from different website, I won't just "forget" that there is a site called Amazon.com. Neither my browser, If I won't wipe the cookies!

I'm fairly sure, that many people are playing the game from earlier versions will end up having all sorts of problems, having all the wrong info (broken stations, broken trading etc) saved in the savegame xml. The game saves everything, so if a factory or farm wasn't working before, it won't be working later either, regardless of how many patches you gonna pile on top of your game.