I do not know if this is a french bug or what, I am playing X3 TC with 1.2.1 patch in french.
I get this bug with all QG missions, QG missions like OTAS (or the one just down Argon Prime, you know the big stations looking like a crown).
All missions for all QG's where I need to execute somenone, I first need to meet a contact. Location of this contact is random, but its name is always "No Pilot".
The problem is, when I get to the location of this "No pilot" guy, there is a "No Pilot" but I cannot contact him ... (my name is nobody joke

Always with the QG missions, sometimes I get an empty mission, means that the detail/briefing of the mission is just an empty window at first look (before accepting it). If I take the mission and then look at the briefing, this time I get a real briefing.
Always with QG mission

Note that I do not have those problems with the millitary QG (the mission line starting with the "Exterminator" guy who wants to avoid invasion in Dark Sun).
I hope this will be fix with the next patch.