btw, you dont need to run it through the pluginmanager very time, once the plugin is installed its installed

a:)
activate the scripts editor:
save and reload the game.
when you it will start to install, if you will see brief messages at the bottom of the screen.
b:)
It is the relation that the pirates guild has towards the teladi. You can change this from neutral to friendly i belive.. This does not directly apply to you though, you need to join up with the pirates guild, and your relation with the teladi is allways your own. (meaning shoot the teladi at your own risk

c:)
The war between the argon and terran cannot be stopped by the IR, you have to modify alot of files inorder to stop that war, which is beyond the scope of IR2.0 at the moment. So if you change the relation between the Argon and terran these will effect the ships, OUTSIDE of the war sectors.
To Stop this war (and add all the missions from Terran Conflict, use the following mod: (thought then you need to start a new game)
http://forum.egosoft.com/viewtopic.php?t=324236
d:)
the war sectors change ownership back and forth between argon and terran, but there are allways hostile ships (Argon<->Terran)in these sectors.
ps: answer:
"Thereshallbewings" needs to be entered, then save and reload the game. This will start the installation of IR2.0
After that, you can find the hotkey to be asigned in:
controls->interface, at the bottom of the list.
Its in red white and yellow, so should be fairly hard to miss

the ECs: Extended Comm, wont work until you have a pirate ship targeted, then it allows for a special menu to be used with pirates.
the IR2.0 hotkey will show up here once you save and reload

Yes, pirates guild works perfectly with IR2.0, however you need to set their difficutly to High, otherwise they are wiped out by IR way to quickly.
Pirate ships and bases are fairly high on IRs todo list.

Meaning, the races will target pirate sectors first (if you dont change said race to neutral or friendly with pirates.
btw, to change the races relationship to eachother, you will find the options in the Hot war menu. in the IR hotkey.
hope that helps =)
/besty